![]() ![]() Schematic dose–response curves for different outcomes for efficacy and adverse effects with inhaled corticosteroids, expressed as fluticasone propionate in µg/day. (Fig.2) 2) therefore, addition of an add-on therapy may be considered to be a more effective and safer treatment strategy 11– 13. In addition, evidence suggests that the ICS dose–response curve is relatively flat, with 80–90% of the maximum achievable therapeutic effect in adult asthma obtained at 200–250 μg of fluticasone propionate or equivalent (Fig. Add-on treatments may therefore be required 9. In addition, most of the clinical benefit of ICS use is seen at low doses. However, if asthma remains uncontrolled despite medium-dose ICS, increasing the dose of ICS may not be appropriate due to an increased risk of local and systemic side effects and variation in individual ICS dose-responsiveness between patients. ![]() Inhaled corticosteroids (ICS) are considered an effective long-term controller treatment in the management of asthma 10. The Global Initiative for Asthma (GINA) strategy recommends a stepwise approach to asthma management in order to achieve symptom control and prevent future risks, including exacerbations, loss of lung function, and side effects of medication (Fig. Reducing asthma symptoms and future risk through correct add-on therapy and management in patients who remain uncontrolled despite treatment is a major challenge for those working in both secondary and primary care. Physicians may underestimate the prevalence and severity of symptoms and overestimate the degree to which the patient’s asthma is controlled, meaning the patient may not receive adequate medication to achieve control of their disease 2, 7. ![]() It has been suggested that patients may overestimate and thus inaccurately report their level of disease control, because they accept and tolerate a certain level of symptoms, assuming them to be an inevitable consequence of asthma 7, 8. Many patients with asthma remain symptomatic, despite treatment, for multiple different reasons 2– 6. This information could aid decision-making in primary care, supporting the use of add-on therapy to ICS to help improve lung function, control asthma symptoms and prevent exacerbations.Īsthma is a serious global health issue that affects all age groups, with a reported 339 million sufferers worldwide, presenting a number of challenges for primary care physicians 1. In children, results were positive and comparable between therapies, but data are scarce. In adults, LAMAs and LABAs provide a greater improvement in lung function than LTRAs as add-on to ICS. We explore the challenges of asthma management in primary care and review outcomes from randomised controlled trials and meta-analyses comparing the long-acting muscarinic antagonist (LAMA) tiotropium with long-acting β 2-agonists (LABAs) or leukotriene receptor antagonists (LTRAs) as add-on to ICS in patients with asthma. However, many patients remain poorly controlled, and evidence-based algorithms to decide on the best order and rationale for add-on therapies are lacking. The Global Initiative for Asthma recommends a stepwise approach to adjust asthma treatment to the needs of individual patients inhaled corticosteroids (ICS) remain the core pharmacological treatment. ![]()
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![]() ![]() Important information regarding the Mac version During the installation a security message will appear because I do not have a developer account. ![]() This program is designed to help you bring order to your Sims 4 mod folder. Pues bien, por suerte existe Mod/CC Manager 2021. Sims 4 Mod/CC Manager 2023 by GameTimeDev V1.2.0. If you’d like to delete bad CC, this is what you’ll have to do: Open the tray importer. Custom Content List of Your Sims Creations. It's located at: \Documents\Electronic Arts\The Sims 4\Mods If the 'Mods' folder is missing, turn the game on and off at least once. Locate The Sims 4 Documents Folder Open the folder for The Sims 4 Mods. Cultura Geek Videojuegos Hogar / Domótica Imagen y Sonido Móviles Ofertas. On the right side, you’ll see 3 tabs on the top of the page, just beside the search box ‘ General ’, ‘ Files ’, and ‘ CC ’. MAC - UNARCHIVER Careful Some Archive Managers won’t extract all files and the mod installation will be incomplete 2. Te explicámos cómo descargarlos e instalarlos en tu PC o Mac. Then open Windows Explorer on PC, or Finder on Mac, and locate Electronic. Mejora tu partida de Los Sims 4 con estos mods imprescindibles. This will typically be in a folder in “ Documents/Electronic Arts/The Sims 4/Mods.” If the “Mods” folder doesn’t exist, you can make your own, as long as it’s in the same location. To install the best Sims 4 mods in your game, all you initially need to do is download any mod file you like the look of. ![]()
![]() ![]() ![]() Think about platform terminology: use the wrong translation for Xbox 360's buttons, use the wrong verb to describe a Wiimote shake, dare to call the PlayStation 3 a console (and not a system) and the game you translate might be forbidden publishing.All of a sudden, it's not only a matter of style, it's making your work viable.Xbench can help. We worked hard to shape it and all the terms inside it are just how they should be. No problem: we select the "Key terms" box and all its results will have a star next to them to be clearly recognizable. Thinking about our translation memories, there's one we really keep in evidence, and that's our glossary. Let's say that we have a tmx with last week's translation, finalized and confirmed by the client, and another one with the work we did yesterday, still a bit rough and work in progress.We want the most reliable results to appear first, and the rest showing only when that possibility is exhausted, and that's precisely what Xbench allows to do.Each translation memory can be set as high, medium or low priority (and its order of appearance be tweaked even further within each class).It may not seem much, but having results to appear in the order we want and color coded by how much we trust them, makes the process even faster and second nature (and that's what we want, when the Xbench window will be called hundreds of times per day!) Xbench allows you to load multiple translation memories and give them a priority. ] One step beyond: priority and key terms A process that took minutes of your time, is now instantaneous and can browse through tens of thousand of words![ Xbench will pop up and show all the sentences that contain it ("Callefosca"!).You are than free to copy and paste what you need. Well, just select the source words you are looking for ("Darskstreets"), then press Ctrl+Alt+Ins (or configure another combination, if you prefer). You are pretty sure that you translated Darskstreets before, but how was it in Italian? "Strade buie"? "Strade oscure"? Now simply fire up Xbench, select Project>New, set the formato to tmx, load the file we just created and we're done!So, let's say that you have another case of amnesia. Then you just set source and target language ("English US" and "Italian" in our case) and the output format (TMX). That's why we usually prefer Tmx, which is solid and widely supported.The process is very simple. The simplest option is to save it as "Unicode text" or "Csv (comma delimited)" directly from Excel, but it may create some problems with line breaks. Then, we just need to convert it in a format supported by Xbench. ![]() Game texts are commonly split in many, small strings, and that's very good for translation memories, because it creates short, accurate entries.All we need to do is take the old translations and put them in a two columns file like this: Let's say that we have already translated the first part of our friend Venetica and that we are ready to start the next. And you dig through your hard disk to find it, then check inside the files, then maybe don't find it at all and you give up, bitter and sad.In both cases, the process slowly gnaws your time and energy.Įnter Xbench. So you need to stop translating, try one or two searches, then finally you can copy your translation, find where out where you left the text and paste. You clearly remember having already translated a word or a sentence (and it was a good translation too!) but you just forgot how. TMBuilder: transforms Excel files into Tmx usable by the above - Concordancing (Update: Apsic has since added a paid version but the free 2.9 build is fine for most people, especially if you don't need Unicode support) If you want to do the same, you just need to download and install these two free programs. I will show step by step how it can be used in order to help your daily work. One of these is surely Apsic Xbench, a free concordancer and QA tool which had a pivoltal role in our team. There are now free and open translation memory tools that can be learned in minutes, giving measurable benefits *in terms of turnarounds, quality and consistency. A common feeling in game localization is that assisted translation tools are too complex and expensive for our needs. ![]() ![]() Quantum Break is perhaps the most perfect synthesis of game and television ever made, but it's also the realization of a dream from another era. Similarly, attempting to marry TV and games has long been something the medium has stumbled towards, ever since they started using live-action videos to break up the pixelated action and help piece together a larger story. Branching, choose-your-own-adventure style narratives are now a staple of video games-a lot of times, games are evaluated by how aware they are of the people who play them how accommodating they are to different proclivities and attention spans. What makes Quantum Break interesting to pick apart is the way it's so squarely built on two phenomena that video games have long fetishized: Player choice, and TV. Ironically, the most interesting stuff is tucked away in the many, many, emails and text excerpts strewn about the game's world, which exhibit the creator's characteristically goofy sense of humor and sometimes serve as a tongue-in-cheek bit of self-deprecation, as well as give the straightforward sci-fi story some much-needed dimension. The plot, like the show, is just good enough to keep you engaged, and the wibbly-wobbly time powers are just fun enough to keep you from getting annoyed whenever a big firefight is thrown your way. For as novel as Quantum Break's approach is, however, its story is only okay. It's not all-encompassing, mind you- Quantum Break is like a train on rails, and the choices you make at certain junctures will take you along a different track, but there are only so many of those, and so much television footage filmed. It's the sort of thing video games have wanted to do for a very long time. Lance Reddick and Aidan Gillen in the 'Quantum Break' show Microsoft/Remedy Entertainment (The game/show is a science fiction thriller, in which Shawn Ashmore plays Jack Joyce, a guy roped into a time-travel experiment by physicist Paul Sereene-played by Aidan "Littlefinger" Gillen-that ends up literally breaking Time Itself, setting up a doomsday scenario and also giving the two of them superpowers.) Smaller things you do in the game make their way to the show as well-maybe you erase a formula from a whiteboard, or find a small statue lying about-those subtle things will be reflected in the next episode you watch. At certain crucial moments, the game offers you a choice from which the game's narrative will split in a dramatic way-the first involves whether or not you will spare someone's life-and the repercussions spill out in both the game and the show. ![]() The show's story changes based on the decisions you make in the video game parts. The miniseries is interspersed with gameplay, so at certain points, you, the player, put down the controller and just watch the action unfold for a bit. ![]() ![]() While a lot of Quantum Break's story unfolds in traditional video game fashion-you shoot and explore, listen to characters chatter, and occasionally watch a scene play out where the CG versions of Shawn Ashmore, Aidan Gillen, et al make big, plot-shifting moves-there's another half that unfolds across a four-part live-action miniseries. Also unlike most other video games, Quantum Break has its big party trick: also being a TV show. ![]() ![]() ![]() Often, the bus announcements themselves are often communicated in Greek, making my own morning commute difficult, especially when bus shelters lack additional signage to indicate where along the route I’ve been let off. By making morning commutes – without a car – possible, the CPT makes it possible for users to arrive at work, make money and pay the bills.īut still, the CPT must continue to update their system so as to make using it easier. A student who prioritised affordable rent over the convenience of commuting, I would, like some of my fellow passengers, be left walking forty-minutes to work each way – in the heat of the summer. ![]() For anyone who is new to Nicosia or is without access to a car, the CPT is crucial for navigating the city. Besides tourists, the vast majority of the CPT’s passengers are migrants, who use English as an intermediary between Greek and their own, native language. These ratings could, in part, be a result of a language barrier, as most non-Cypriot commuters rely on English to navigate the city’s bus system. These sentiments are evidenced in the following mean scores for the subcategories of Operators’ Staff Behaviour and Passenger Information offered: 3.69/5 and 2.93/5, respectively. Passengers ultimately felt overlooked and poorly communicated with by the system’s operating staff. In a 2022 service satisfaction survey, the CPT reported an overall 8.05/10 satisfaction rate among users in Nicosia, and yet, in the survey’s subcategories (those created to analyse interactions between the community members that CPT supposedly works to unite), scores were particularly low. The CPT’s commitment to serve Nicosia’s community is ironic considering that city buses are typically used by non-natives. Because of its recent efforts to expand, this modernised, public transportation system seems to have earned its online slogan: “our success is everyone’s success.”Īnd yet, in the eyes of Cypriots, the system still falls flat. Working closely with a ministry that prioritises going green, the CPT recently welcomed its first line of electric buses, which will hit the roads after a company celebration on July 4. Supplying a fleet of buses that provide 5G service to its users, the CPT, since it was revamped in 2021, is of a higher calibre than the system that went before. ![]() “ The bus system has evolved and now offers a better situation than it did before,” Alexander Kamberos, CPT’s business development manager, reminds readers. But to make my daily commute from Solomou Square to the office, CPT has, inevitably, become a transportation lifeline for me – and will continue to be for the duration of my two-month stay. “ Rent a car,” I’ve been told, until I remind Cypriots that I’m American and, therefore, used to driving on the other side of the road. ![]() ![]() ![]() Some people use Bubble Wrap to play Twister After the dessert has set, she pops each one out of the makeshift mold to create dozens of dome-shaped shots.Ĥ7. Morena DIY uses a syringe to inject liquid Jell-O into a piece of Bubble Wrap with a large bubble size. (Or at least, demand for bubble wrap suits suddenly existed.) If you can’t live without one, you can purchase the poppable attire for the surprisingly affordable price of $24.99. You can purchase a “bubble wrap suit.” After Ashton Kutcher and Seann William Scott donned bubble wrap suits in the cult movie Dude, Where’s My Car?, demand for bubble wrap suits skyrocketed. In 2017, a South Carolina man used Bubble Wrap as a murder weapon. Bubble Wrap has been used as a murder weapon.īut seriously, it really can kill. “ Kerblam!,” an episode of Doctor Who that aired in November 2018, introduced viewers to lethal Bubble Wrap. The “ Popping Bubble Wrap” Facebook group has 460,000 members. Bubble Wrap has a massive online following. In response to concerns about sustainability, the university issued a statement saying that the stunt was a clever way to reuse packing material that university furniture had come in. In 2019, The University of Bristol in England provided students with squares of Bubble Wrap to help relieve anxiety. The Bubble Wrap manufacturer isn’t the only organization to see the value in stress-popping. Higher learning institutions recognize Bubble Wrap's mental health benefits, too. (No word on whether this is still standard practice.) 41. Sealed Air employees know the value of Bubble Wrap's stress relief.Īccording to The New York Times, at one point, employees at Sealed Air each received a small box of individual squares of Bubble Wrap to keep at their desks for emergency stress relief. Other honorees include Thomas Edison and Albert Einstein. ![]() In 1993, inventors Marc Chavannes and Alfred Fielding received a coveted spot in the New Jersey Inventors Hall of Fame for their Bubble Wrap contributions. Bubble Wrap's inventors are in the New Jersey inventors Hall of Fame. Dermot Dunphy was named CEO, and under his direction, the firm grew to $3 billion in sales by the time he left in 2000. Until 1971, Sealed Air was a relatively modest company, turning a profit of just $5 million. The bubbles were a lot bigger then, so they made a loud noise.” 38. The adults at my father’s firm likely did so for quality assurance. “I say I’m the first person to pop Bubble Wrap, but I’m sure it’s not true. “I remember looking at the stuff and my instinct was to squeeze it,” Fielding told Smithsonian Magazine. The first person to pop bubble wrap: Howard Fielding, the inventor’s son. The inventor's son was the first non-adult to pop it. (No, they’re not as good as the real thing.) 37. There are Bubble Wrap apps.īoth iPhone and Android offer Bubble Wrap apps. In 2012, the Bubble Wrap® Brand “Pop” Poll surveyed respondents and found that one minute of bubble-popping provides the stress relief equivalent to a 33-minute massage. You’re not imagining the psychological, stress-relieving benefits that come with popping Bubble Wrap. ![]() Bubble Wrap might be as good as a massage. They claim to be the company that invented vacuum sealing. ![]() Bubble Wrap is Cryovac's cousin.Īmong other things, the Sealed Air company also owns Cryovac, a thin plastic that is shrink-wrapped around food and other items. They’ve diversified their portfolio to include products like medical packaging solutions and a diverse array of food packaging products. Still, today, Bubble Wrap makes up just 2 percent of the Sealed Air’s sales. Bubble Wrap is hardly the only product that Sealed Air makes. Every year, enough of the poppable stuff is made that it could wrap around the equator 10 times, or make it to the moon and back. Bubble Wrap is made in 52 countries, and there's a lot of it.īubble Wrap is made in 52 countries. When it comes to shipping, smaller bubbles keep items protected from scratches and scrapes, while larger bubbles are more effective for preventing damage from impact. It comes in bubble sizes that range from 1/8” to 3/16”. Chocolatiers and bakers use this technique to create luxurious and impressive-looking treats and garnishes with very little time and effort. Spreading melted chocolate on a piece of Bubble Wrap and letting it harden creates a honeycomb-like pattern when the wrap is peeled off. ![]() ![]() ![]() So when it comes to relationships, should we look to the planets to lead the way in a deterministic fashion? The answer, according to Brownstone, is yes. To bring clarity to our skies, Certified Professional Consulting Astrologer Diana Brownstone weighs in to help us better understand the widely oversimplified discipline: The typical 12-sign blanket descriptors do a disservice to astrology, only representing a superficial sampling of the very complicated discipline. So, regardless of your set of beliefs, one thing is certain: if you choose to follow the stars-you must do so properly. You, sir, have not.” And when Newton speaks, we listen. However, as Sir Isaac Newton, the father of physics, once said in defense of astrology to skeptic Edmund Halley, “I have studied the matter. ![]() ![]() But sprinkle in a little modern science, add a touch of wishful thinking, and you might realize that you are only prey to your own premeditations. And who can blame anyone for taking a cue or two from these brilliant figures, especially when your last three boyfriends have all been Leos? Admittedly, the thought of having some sense of control over your own destiny is a tasty one. Yet the debate stubbornly remains the same: Is it in the stars? Or is in your head? Shakespeare, Chaucer, and Hippocrates all seemed to favor the idea of an unalterable, inescapable, predestined fate between two lovers, a knot tied sternly together by the gods, if you will. Star-crossed lovers: The phrase has made waves through the centuries. ![]() ![]() ![]() So I gave the new address and I sent them a document. On the page where you have to submit a document to prove address Paypal gives you an option to insert a new address if you want, which is nice. So I took out my passport – valid with all my real information – I took a screenshot and I sent that photo to Paypal.įor verifying my address I first had to change the address on my Paypal account, because the address I had on record was outdated. There was no note about translation or anything like that. However, upon choosing ID on Paypal, I was greeted with a note that said I had to find a licensed translator and translate the ID and then take a screenshot of that and send it to them. I logged in, and then I was taken to a page where I had to submit 1 document to verify my Identity, and 1 document to verify my address.įor verifying my identity I first took a screenshot of my ID, and I went to submit it. So I clicked on the “ Confirm Your Identity” link, and I was taken to the Paypal login page. For details, please refer to our Privacy Policy. The information you provide will be protected. Please confirm your identity at your earliest convenience. Just click the button below to provide the required documents. Please provide more information to confirm your identity. You’re about to reach your account balance limit. As part of our continuous efforts in delivering this commitment and complying with regulatory requirements, we need you to confirm your identity at a particular milestone with us. Providing our customers with a safer payment environment is important to us. Thank you for choosing PayPal as your preferred way to pay and get paid. One day I was just sitting there, not bothering anybody, and I receive an email from Paypal. In this post I’ll show you exactly the steps and the process, what documents I submitted, the problems I encountered and the solutions. ![]() I was expecting this to happen at some point as money flows through the account and as the account ages, and it happened. ![]() A little while ago I was asked to confirm my identity on my almost 3 year old Paypal account. ![]() ![]() Our showroom and waiting area was designed with your comfort in mind, so you’ll feel right at home the moment you arrive. Ready to put adventure on the agenda? Visit RedLine Powersports Myrtle Beach today! Our deep commitment to quality is evident in all we do, and we can’t wait to prove it! For unrivaled selected and exceptional customer service, we are your one-stop shop. Schedule a service appointment today! Visit Us Today! Whether it’s time for a simple oil change, tire replacement, or a more complex repair, our team of certified technicians is eager to get to work. Looking to DIY? Order your parts online and we'll let you know when they're available to be picked up! If you’re looking to upgrade or customize your ride, we can help with that too! Our Parts Department carries a wide range of components and accessories to fit your vehicle. And to maintain peak performance, no matter where you roam, we use only genuine OEM parts. We’ve made it easier than ever to keep your vehicle running right, with our Service Center providing quick, convenient maintenance and repairs. To ensure your powersports vehicle is always adventure-ready, routine maintenance is required. We’ve also provided financing incentives to make the most of your budget, including new specials and lease offers – so be sure to check them out! Count On Us For Your Service & Repair Needs Planning to sell or trade in a vehicle? Estimate your vehicle’s value in 30 seconds with just a couple of clicks! You can even compare models and financing options from home, using our payment calculator to estimate monthly payments for each. To save time here at our powersports dealership, complete our online financing application. Our specialists will guide you through our simple, stress-free process, offering several financing options to make your dream powersports vehicle a reality. Once you’ve found the right new or used motorcycle, ATV, or jet ski, financing comes next. Let’s get started! Fast and Easy Financing Our friendly, knowledgeable sales team will help you find the perfect new or used powersports vehicle, whether you’re just starting your search or have your eye on a specific model. We carry a diverse range of brands, including Yamaha, Can-Am, Honda, Kawasaki, Sea-Doo, Polaris, and more.īrowse our new inventory online or stop by for a tour of our state-of-the-art showroom. In addition to an unmatched selection, our team provides the highest standard of customer service – so it’s no wonder locals call us their trusted Myrtle Beach powersports dealer! Our sales and service professionals are eager to put our experience to work for you, so come see us today! Our Extensive New and Pre-Owned Inventoryįor an incredible selection of fun-to-drive powersports vehicles, locals know where to go: RedLine Myrtle Beach! Whether you’re looking for a motorcycle, ATV, UTV, or personal watercraft, we’ve got you covered. You will also find a wide range of boating accessories, including trolling motors, GPS systems, fishfinders, ropes, anchors and life jackets in our on-site store.Your Local Powersports Dealer in Myrtle Beach, SCįrom the wilderness to the waves, powersports vehicles are equipped for exploring – and your next great adventure begins at RedLine Powersports Myrtle Beach! We’ve stocked a wide variety of powersports vehicles and accessories, ensuring you’re ready to tackle any terrain. Whether you are looking for a boat to fish, entertain, explore or just relax, our professional sales team will direct you to the watercraft that best meets your needs. This passion is shared by employees Ryan Ritchie (Service Manager), Duran Carlson & Carson Dani in ATVs and Ryan Schmidt in marine.įor the water – Redline Sport and Marine sells G3 boats and SunCatcher pontoons that meet high standards for safety and reliability. Ben, an avid outdoorsman and President of UPROAR purchased the business in 2022 and with his unique experience and drive for success is building on the reputation for customer care that has been the foundation of Redline. Jared Gendron founded Redline in 2010 with over 20-years of experience in the industry and a love for the business he inherited from his family. It is what sets Redline Sport and Marine apart from other dealerships. ![]() These are the values embraced by Redline’s owner, Ben Peterson, and reflected in the work of all Redline employees. ![]() |
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